Invitrogen™ GluR2/GluR3 Recombinant Rabbit Monoclonal Antibody (4C3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA549790

Catalog No. FEMA549790

Description

GluR2/GluR3 Recombinant Monoclonal Antibody for ICC/IF, ELISA

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Specifications

• Antigen: GluR2/GluR3
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P42262, P42263
• Gene Symbols: Gria2, Gria3
• Immunogen: A synthesized peptide derived from human GRIA2/GRIA3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunocytochemistry
• Clone: 4C3
• Conjugate: Unconjugated
• Gene: Gria2
• Gene Alias: 2900064I19Rik; AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA2; GluA3; GLUR2; GluR-2; GLUR3; GluR-3; Gluralpha3; GLURB; gluR-B; GLURC; GLUR-C; GluR-K2; GluR-K3; glutamate ionotropic receptor AMPA type subunit 2; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 2; Glutamate receptor 3; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor C; glutamate receptor channel alpha3 subunit; glutamate receptor ionotropic, AMPA 2; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA2 (alpha 2); glutamate receptor, ionotropic, AMPA3 (alpha 3); GPRC1C; GRIA2; GRIA3; GRM3; HBGR2; Kiaa4184; MGR3; MRX94
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2891, 2892
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid