Invitrogen™ GluR2 Recombinant Rabbit Monoclonal Antibody (9R1X2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535096

Catalog No. PIMA535096

Description

Immunogen sequence: YLYDSDRGLS TLQAVLDSAA EKKWQVTAIN VGNINNDKKD EMYRSLFQDL ELKKERRVIL DCERDKVNDI VDQVITIGKH VKGYHYIIAN LGFTDGDLLK I.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.

Specifications

• Antigen: GluR2
• Classification: Recombinant Monoclonal
• Concentration: 1.3 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P19491, P23819, P42262
• Gene Symbols: Gria2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GluR2/GRIA2 (P42262).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 9R1X2
• Conjugate: Unconjugated
• Gene: Gria2
• Gene Alias: AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; GluA2; Glur2; GluR-2; GLURB; GluR-B; GluR-K2; glutamate ionotropic receptor AMPA type subunit 2; glutamate receptor; glutamate receptor 2; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA2 (alpha 2); GRIA2; HBGR2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14800, 2891, 29627
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov