Invitrogen™ GluR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588158

Catalog No. PIPA588158

Description

Positive Samples: U-251MG, PC-3, Mouse brain, Mouse lung; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse Immunogen sequence: QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Specifications

• Antigen: GluR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIA3
• Gene Alias: 2900064I19Rik; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA3; GLUR3; Glur-3; Gluralpha3; GLURC; GLUR-C; GluR-K3; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 3; glutamate receptor C; glutamate receptor channel alpha3 subunit; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3); GRIA3; Kiaa4184; LOW QUALITY PROTEIN: glutamate receptor 3; MRX94; OTTHUMP00000024262; RP11-349N19.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2892, 53623
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Western Blot
• Concentration: 0.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P42263, Q9Z2W9
• Gene Symbols: GRIA3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-490 of human GRIA3 (NP_0008193).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG