Invitrogen™ GluR3 Polyclonal Antibody

Catalog No.	Quantity
PIPA588158	100 μL

Catalog No. PIPA588158 Supplier Invitrogen™ Supplier No. PA588158

Description

Rabbit Polyclonal Antibody

Positive Samples: U-251MG, PC-3, Mouse brain, Mouse lung; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse Immunogen sequence: QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Specifications

• Antigen: GluR3
• Applications: ELISA, Western Blot, Western Blot
• Classification: Polyclonal
• Concentration: 0.36 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GRIA3
• Gene Accession No.: P42263, Q9Z2W9
• Gene Alias: 2900064I19Rik; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA3; GLUR3; Glur-3; Gluralpha3; GLURC; GLUR-C; GluR-K3; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 3; glutamate receptor C; glutamate receptor channel alpha3 subunit; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3); GRIA3; Kiaa4184; LOW QUALITY PROTEIN: glutamate receptor 3; MRX94; OTTHUMP00000024262; RP11-349N19.3
• Gene Symbols: GRIA3
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-490 of human GRIA3 (NP_0008193).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2892, 53623
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG