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Invitrogen™ GluR4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5144906
Description
Immunogen sequence: NGWHVSAICV ENFNDVSYRQ LLEELDRRQE KKFVIDCEIE RLQNILEQIV SVGK Antigen sequence identity: Mouse 100%; Rat 100%.
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
Specifications
GluR4 | |
Polyclonal | |
Unconjugated | |
Gria4 | |
AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1 | |
Rabbit | |
Affinity chromatography | |
RUO | |
2893 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid | |
IgG |
Immunocytochemistry | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P48058 | |
Gria4 | |
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 177-230. Recombinant protein control fragment (Product #RP-109960). | |
100 μL | |
Primary | |
Human | |
Antibody | |
Liquid |
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