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Invitrogen™ GluR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144906

Catalog No. FEPA5144906


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Description

Description

Immunogen sequence: NGWHVSAICV ENFNDVSYRQ LLEELDRRQE KKFVIDCEIE RLQNILEQIV SVGK Antigen sequence identity: Mouse 100%; Rat 100%.

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GluR4
Polyclonal
Unconjugated
Gria4
AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1
Rabbit
Affinity chromatography
RUO
2893
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
IgG
Immunocytochemistry
0.3 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P48058
Gria4
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 177-230. Recombinant protein control fragment (Product #RP-109960).
100 μL
Primary
Human
Antibody
Liquid
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