Invitrogen™ GluR4 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518931

Catalog No. PIPA518931

Description

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.

Specifications

• Antigen: GluR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gria4
• Gene Alias: AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 2893
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P48058
• Gene Symbols: Gria4
• Immunogen: Synthetic peptide sequence (KKLDQREYPGSETP) corresponding to the internal amino acids of GRIA4 (aa 280-294).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG