Glut1 Antibody (GLUT1/2476), DyLight 650, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275787C

Catalog No. NB009249

Description

Glut1 Monoclonal specifically detects Glut1 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Glut1
• Classification: Monoclonal
• Conjugate: DyLight 650
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: SLC2A1
• Immunogen: Recombinant fragment of human Glut1 protein (around aa 203-305) (exact sequence is proprietary) (Uniprot: P11166)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG2b κ

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: GLUT1/2476
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Gene Alias: Choreoathetosis/Spasticity, Episodic (Paroxysmal Choreoathetosis), CSE, DYT17, DYT18, DYT9, EIG12, Glucose transporter type 1, erythrocyte/brain, GLUT-1, GLUT1DS, HepG2 glucose transporter, HTLVR, Human T-Cell Leukemia Virus (I and II) Receptor, MGC141895, MGC141896, PED, solute carrier family 2 (facilitated glucose transporter), member 1, Solute Carrier Family 2 Member 1, solute carrier family 2, facilitated glucose transporter member 1
• Host Species: Mouse
• Molecular Weight of Antigen: 54.1 kDa
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cardiovascular Biology, Cellular Markers, Diabetes Research, Lipid and Metabolism, Membrane Trafficking and Chaperones, Neuroscience, Plasma Membrane Markers, Signal Transduction
• Test Specificity: Recognizes a protein of 54.1 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).
• Content And Storage: Store at 4°C in the dark.