Invitrogen™ Glutaminase C (GAC) Monoclonal Antibody (GT1075)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531537

Catalog No. PIMA531537

Description

Keep as concentrated solution. Predicted reactivity: Bovine (100%). Positive Control: MCF-7, MDA-MB-231. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

Specifications

• Antigen: Glutaminase C (GAC)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O94925
• Gene Symbols: GLS
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Glutaminase C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot, Immunocytochemistry
• Clone: GT1075
• Conjugate: Unconjugated
• Gene: GLS
• Gene Alias: 6330442B14; AAD20; AI314027; B230365M23Rik; GAC; GAM; GLS; Gls1; Glut; glutaminase; glutaminase C; glutaminase kidney isoform, mitochondrial; Glutaminase kidney isoform, mitochondrial 65 kDa chain; Glutaminase kidney isoform, mitochondrial 68 kDa chain; glutaminase, phosphate-activated; KGA; K-glutaminase; KIAA0838; L-glutamine amidohydrolase; RATGLUT
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2744
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid