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Invitrogen™ Glutaminase C (GAC) Polyclonal Antibody
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Catalog No. PA540135
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100 μL
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PA540135 100 μL
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Catalog No. PA540135 Supplier Invitrogen™ Supplier No. PA540135
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Rabbit Polyclonal Antibody

This antibody specifically recognizes GAC but not the KGA isoform. Predicted reactivity: Bovine (100%). Recommended positive controls: MDA-MB-231 cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glutaminase C (GAC)
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.96 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene GLS
Gene Accession No. O94925
Gene Alias 6330442B14; AAD20; AI314027; B230365M23Rik; GAC; GAM; GLS; Gls1; Glut; glutaminase; glutaminase C; glutaminase kidney isoform, mitochondrial; Glutaminase kidney isoform, mitochondrial 65 kDa chain; Glutaminase kidney isoform, mitochondrial 68 kDa chain; glutaminase, phosphate-activated; KGA; K-glutaminase; KIAA0838; L-glutamine amidohydrolase; RATGLUT
Gene Symbols GLS
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Glutaminase C (GAC). The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2744
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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