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Glutamine Synthetase Mouse anti-Human, Mouse, Rat, Clone: GT7711, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527750

Catalog No. PIMA527750


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Description

Description

Positive Control: 293T, A431, HeLa, HepG2, mouse brain, rat brain, mouse eye Predicted Reactivity: Xenopus laevis (85%), Dog (97%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer ft.s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
Specifications

Specifications

Glutamine Synthetase
Monoclonal
1.0 mg/mL
PBS with no preservative
P09606, P15104, P15105
glutamate-ammonia ligase, GLNS, GS, PIG59, PIG43, GLUL
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14645, 24957, 2752
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
GT7711
Unconjugated
GLUL
Liquid
Glul
Full length human Glutamine synthetase Recombit protein.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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