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Invitrogen™ CEP104 Polyclonal Antibody
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Catalog No. PIPA5110760
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PIPA5110760 100 μL
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Catalog No. PIPA5110760 Supplier Invitrogen™ Supplier No. PA5110760
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Rabbit Polyclonal Antibody

Immunogen sequence: EIVLQMVERC RIRKLQLLAH QYMISSKIEF YISESLPEYF APYQAERFRR LGYVSLCDNE KTGCKARELK SVYVDAVGQF LKLIFHQNHV NKYNIYNQVA LVAINIIGDP ADFSDESNTA SREKLIDHYL Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 91%.

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEP104
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CEP104
Gene Accession No. O60308
Gene Alias A930027E11; AI115523; centrosomal protein 104; centrosomal protein 104kDa; centrosomal protein of 104 kDa; CEP104; CFAP256; Gly-, L-Glu and TCP-binding protein; GlyBP; Glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein; glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; JBTS25; Kiaa0562; likely ortholog of H. sapiens glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; mKIAA0562; ROC22
Gene Symbols CEP104
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human CEP104. Recombinant protein control fragment (Product #RP-88839).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9731
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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