Invitrogen™ CEP104 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110760

Catalog No. PIPA5110760

Description

Immunogen sequence: EIVLQMVERC RIRKLQLLAH QYMISSKIEF YISESLPEYF APYQAERFRR LGYVSLCDNE KTGCKARELK SVYVDAVGQF LKLIFHQNHV NKYNIYNQVA LVAINIIGDP ADFSDESNTA SREKLIDHYL.

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization.

Specifications

• Antigen: CEP104
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60308
• Gene Symbols: CEP104
• Immunogen: Recombinant Protein corresonding to Human CEP104. Recombinant protein control fragment (Product #RP-88839).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene: CEP104
• Gene Alias: A930027E11; AI115523; centrosomal protein 104; centrosomal protein 104kDa; centrosomal protein of 104 kDa; CEP104; CFAP256; Gly-, L-Glu and TCP-binding protein; GlyBP; Glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein; glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; JBTS25; Kiaa0562; likely ortholog of H. sapiens glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; mKIAA0562; ROC22
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9731
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov