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Description
Glycine does not have a chiral center, so it is the only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids. It acs as inhibitory neurotransmitter that is shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. It is also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.
Glycine is commonly used as a component in:
- Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis
- Towbin's transfer buffer for Western blots
- Buffers used in cryoenzymology, osmotic pressure maintenance in isoelectric focusing of erythrocytes and salting-in effect in protein chemistry
- Buffer for coupled phosphatase-kinase reaction for end labelling of restriction fragments
Specifications
Specifications
| Solubility Information | Soluble in water (250mg/mL at 25°C; 672mg/mL at 100°C); slightly soluble in alcohol and ethanol (95%); almost insoluble in ether. |
| Quantity | 500 g |
| Formula Weight | 75.07 |
| Percent Purity | ≥98% |
| Physical Form | Powder |
Safety and Handling
| Recommended Storage | Store at Room Temperature (15–30°C). |
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