Glycine, MP Biomedicals™

Description

Can be synthesized in the body by Serine Hydroxymethyltransferase. Glycine, MP Biomedicals is a nonessential, non-chiral amino acid that acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. It is commonly used as a buffer compon

Glycine does not have a chiral center, so it is the only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids. It acs as inhibitory neurotransmitter that is shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. It is also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.

Glycine is commonly used as a component in:

• Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis
• Towbin's transfer buffer for Western blots
• Buffers used in cryoenzymology, osmotic pressure maintenance in isoelectric focusing of erythrocytes and salting-in effect in protein chemistry
• Buffer for coupled phosphatase-kinase reaction for end labelling of restriction fragments

Specifications

Chemical Identifiers

• CAS: 56-40-6
• Molecular Formula: C2H5NO2
• Molecular Weight (g/mol): 75.07
• MDL Number: MFCD00008131
• InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Synonym: glycine, aminoacetic acid, glycocoll, aminoethanoic acid, glycolixir, glycosthene, aciport, glicoamin, padil, hampshire glycine
• PubChem CID: 750
• ChEBI: CHEBI:15428
• IUPAC Name: 2-aminoacetic acid
• SMILES: NCC(O)=O

• Solubility Information: Soluble in water (250mg/mL at 25°C; 672mg/mL at 100°C); slightly soluble in alcohol and ethanol (95%); almost insoluble in ether.
• Quantity: 500 g
• Formula Weight: 75.07
• Percent Purity: ≥98%
• Physical Form: Powder

Safety and Handling

Recommended Storage

Store at Room Temperature (15–30°C).

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