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Glycine, MP Biomedicals™

Catalog No. MP21005705 Shop All MP Biomedicals, Inc Products
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Catalog No. MP21005705 Supplier MP Biomedicals, Inc Supplier No. 02100570.5
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Can be synthesized in the body by Serine Hydroxymethyltransferase. Glycine, MP Biomedicals is a nonessential, non-chiral amino acid that acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. It is commonly used as a buffer compon

Glycine does not have a chiral center, so it is the only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids. It acs as inhibitory neurotransmitter that is shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. It is also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.

Glycine is commonly used as a component in:

  • Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis
  • Towbin's transfer buffer for Western blots
  • Buffers used in cryoenzymology, osmotic pressure maintenance in isoelectric focusing of erythrocytes and salting-in effect in protein chemistry
  • Buffer for coupled phosphatase-kinase reaction for end labelling of restriction fragments
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 56-40-6
Molecular Formula C2H5NO2
Molecular Weight (g/mol) 75.07
MDL Number MFCD00008131
InChI Key DHMQDGOQFOQNFH-UHFFFAOYSA-N
Synonym glycine, aminoacetic acid, glycocoll, aminoethanoic acid, glycolixir, glycosthene, aciport, glicoamin, padil, hampshire glycine
PubChem CID 750
ChEBI CHEBI:15428
IUPAC Name 2-aminoacetic acid
SMILES NCC(O)=O

Specifications

Solubility Information Soluble in water (250mg/mL at 25°C; 672mg/mL at 100°C); slightly soluble in alcohol and ethanol (95%); almost insoluble in ether.
Quantity 500 g
Formula Weight 75.07
Percent Purity ≥98%
Physical Form Powder
Recommended Storage Store at Room Temperature (15–30°C).
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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