Glycophorin A Mouse, Clone: A63-B/C2, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP247716B	Novus Biologicals NBP2477160.2MG	0.2 mg

Description

Glycophorin A Monoclonal antibody specifically detects Antigen in Bovine, Human samples. It is validated for Agglutination, Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: Glycophorin A
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry, Immunofluorescence, Agglutination, CyTOF
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cancer, Signal Transduction
• Formulation: PBS with No Preservative
• Gene ID (Entrez): 2993
• Immunogen: Human erythrocytes treated with neuraminidase
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Molecular Weight of Antigen: 39 kDa

• Clone: A63-B/C2
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Erythrocyte Agglutination, CyTOF-ready
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Bovine
• Gene Alias: CD235a antigen, glycophorin A (includes MN blood group), glycophorin A (MNS blood group), glycophorin Erik, glycophorin MiI, glycophorin MiIII, glycophorin MiV, glycophorin MiX, glycophorin SAT, glycophorin Sta type C, glycophorin-A, GPA, GPErik, GpMiIII, GPSAT, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), Mi.V glycoprotein (24 AA), MN sialoglycoprotein, MNS, PAS-2, recombinant glycophorin A-B Miltenberger-DR
• Gene Symbols: GYPA
• Isotype: IgM κ
• Purification Method: Protein A or G purified
• Test Specificity: Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.