GP6 Monoclonal Antibody (HY101), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen 50981342

Catalog No. 50-112-4554

Description

Description: The HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62-kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation. Applications Reported: This HY101 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HY101 antibody has been pre-titrated and tested by flow cytometric analysis of normal human platelets. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

GP6 Monoclonal antibody specifically detects GP6 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: GP6
• Classification: Monoclonal
• Concentration: 5 μL/Test
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q9HCN6
• Gene Symbols: GP6
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51206
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: HY101
• Conjugate: eFluor 660
• Gene: GP6
• Gene Alias: 9830166G18Rik; BDPLT11; Glycoprotein 5; glycoprotein 6; glycoprotein 6 (platelet); glycoprotein VI (platelet); glycoprotein VI platelet; Gm469; GP6; GPIV; GPVI; platelet collagen receptor; platelet glycoprotein VI
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

For Research Use Only.