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Invitrogen™ Glypican 3 Recombinant Rabbit Monoclonal Antibody (7M2X9)
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Catalog No. PIMA535154
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PIMA535154 100 μL
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Catalog No. PIMA535154 Supplier Invitrogen™ Supplier No. MA535154
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Description

Rabbit Recombinant Monoclonal Antibody

Glypican 3 Recombinant Monoclonal Antibody for ELISA, ICC/IF, Western Blot

GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glypican 3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7M2X9
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene GPC3
Gene Accession No. P51654
Gene Alias defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1
Gene Symbols GPC3
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2719
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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