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Invitrogen™ GLYR1 Polyclonal Antibody
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Catalog No. PIPA5121221
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100 μL
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PIPA5121221 100 μL
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Catalog No. PIPA5121221 Supplier Invitrogen™ Supplier No. PA5121221
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, Mouse brain, Rat testis. The target is usually found in the following locations: Nucleus. Immunogen sequence: MIKINKGKRF QQAVDAVEEF LRRAKGKDQT SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS GSSERGSKSP LKRAQEQSPR KRGRPPKDEK DLTIPESSTV KGMMAGPMAA FKWQPTASEP VKDADPHFHH FLLSQTEKPA VCYQAITKKL KICEEETGST SIQAADSTAV NGSITPTDKK I.

GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLYR1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GLYR1
Gene Accession No. Q49A26, Q5RKH0, Q922P9
Gene Alias 2810419J22Rik; 3930401k13rik; 3-hydroxyisobutyrate dehydrogenase-like protein; AW545332; BM045; Cytokine-like nuclear factor N-PAC; glyoxylate reductase 1 homolog; glyoxylate reductase 1 homolog (Arabidopsis); GLYR1; HIBDL; hNDF; NDF; NP60; Npac; N-pac; nuclear protein 60 kDa; nuclear protein 60kDa; nuclear protein NP60; Nuclear protein of 60 kDa; Nucleosome-destabilizing factor; Putative oxidoreductase GLYR1; RGD1309459
Gene Symbols GLYR1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-270 of human GLYR1 (NP_115958.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 360477, 74022, 84656
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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