GlyT1 (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA577456

Catalog No. PIPA577456

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predomitly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.

Specifications

• Antigen: GlyT1 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC6A9
• Gene Alias: SLC6A9
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116509, 14664, 6536
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P28571, P28572, P48067
• Gene Symbols: Slc6a9
• Immunogen: Peptide (C)RLYVLKLSDDIGD, corresponding to amino acid residues 202-214 of rat Glycine Transporter 1
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG