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Invitrogen™ Human GM-CSF ProQuantum Immunoassay Kit
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Catalog No. p-7161498
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Quantity:
5 x 96 Tests
96 Tests

ELISA

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
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Specifications

Accession Number P04141
Assay Range 0.064 to 5000 pg/mL
Assay Sensitivity <0.05 pg/mL
Conjugate FAM™
Detection Method Taqman™ Real-time PCR
Immunoassay Kit Format Proximity-based Immunoassay
Product Type ProQuantum
Sample Type Plasma, Serum, Supernatant
Target Species Human
For Use With (Application) Protein Quantitation
For Use With (Equipment) qPCR Instruments
Gene ID (Entrez) 1437
Incubation Time 1 hr.
Kit Contents Assay Dilution Buffer, Antibody-Conjugate A, Antibody-Conjugate B, Antibody-Conjugate Dilution Buffer, Standard, Master Mix, Ligase
Label or Dye FAM™
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 2-5 μL, Plasma 2-5 μL, Serum 2-5 μL, Supernatant 2-5 μL
Storage Requirements Frozen at -20°C
Target GM-CSF
Test Time 30 mins
Total Assay Time 2 hrs
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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