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Invitrogen™ GM-CSF Monoclonal Antibody (2B8)
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Catalog No. PIMA549394
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PIMA549394 100 μL
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Catalog No. PIMA549394 Supplier Invitrogen™ Supplier No. MA549394
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Description

Mouse Monoclonal Antibody

This product was used in both Indirect and Sandwich ELISA. This product does not cross-react with human IL1B, IL-2, IL4, IL5, IL6, IL7, CXCL8, IL9, IL10, IL11, IL12, IL13, IL17A, IFNA, IFNG, CCL2, KITLG and TNF. This product can be paired with MA5-49393.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
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Specifications

Antigen GM-CSF
Applications ELISA
Classification Monoclonal
Clone 2B8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene CSF2
Gene Accession No. P04141
Gene Alias colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Gene Symbols CSF2
Host Species Mouse
Immunogen Recombinant Human CSF2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1437
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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