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Invitrogen™ GM-CSF Monoclonal Antibody (3D3)
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Catalog No. PIMA515614
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100 μL
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Catalog No. Quantity
PIMA515614 100 μL
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Catalog No. PIMA515614 Supplier Invitrogen™ Supplier No. MA515614
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Description

Mouse Monoclonal Antibody

MA5-15614 targets CSF2 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15614 immunogen is purified recombinant fragment of human CSF2 (aa18-144) expressed in E. Coli.. MA5-15614 detects CSF2 which has a predicted molecular weight of approximately 16kDa.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
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Specifications

Antigen GM-CSF
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3D3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene CSF2
Gene Accession No. P04141
Gene Alias colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Gene Symbols CSF2
Host Species Mouse
Immunogen Purified recombinant fragment of human CSF2 (aa18-144) expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1437
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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