Invitrogen™ GM-CSF Monoclonal Antibody (404CE 14G12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ AHC2812

Catalog No. AHC2812

Description

This antibody can be used as a capture antibody in ELISA applications. This clone can also be referred to as clone number 404CE 14G12 L1.

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Specifications

• Antigen: GM-CSF
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5mg/mL sodium azide; pH 7.4
• Gene Accession No.: P04141
• Gene Symbols: CSF2
• Immunogen: Purified recombinant human GM-CSF.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 404CE 14G12
• Conjugate: Unconjugated
• Gene: CSF2
• Gene Alias: colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1437
• Content And Storage: 4°C
• Form: Liquid