Invitrogen™ GM130 Monoclonal Antibody (M342)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA547668

Catalog No. PIMA547668

Description

This antibody detects a 130 kDa* protein corresponding to the apparent molecular mass of GM130 on SDS-PAGE immunoblots of mouse C2C12 cells. In immunocytochemistry, anti-GM130 specifically stains Golgi in mouse C2C12 cells.

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.

Specifications

• Antigen: GM130
• Classification: Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: Q08379, Q62839, Q921M4
• Gene Symbols: Golga2
• Immunogen: Clone M342 was generated from a recombinant protein corresponding to amino acid residues in the C-terminal region of human GM130. This sequence has high homology to similar regions in rat and mouse GM130.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry
• Clone: M342
• Conjugate: Unconjugated
• Gene: Golga2
• Gene Alias: 130 kDa cis-Golgi matrix protein; AW555139; cis-Golgi matrix protein GM130; Gm130; GM130 autoantigen; GOLGA2; golgi autoantigen, golgin subfamily a, 2; Golgi matrix protein GM130; golgin A2; Golgin subfamily A member 2; Golgin subfamily A member 2; LOW QUALITY PROTEIN: golgin subfamily A member 2; golgin-95; mKIAA4150; RP11-395P17.5; SY11 protein
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2801, 64528, 99412
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid