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Invitrogen™ GM2A Polyclonal Antibody
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Catalog No. PIPA582333
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100 μL
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PIPA582333 100 μL
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Catalog No. PIPA582333 Supplier Invitrogen™ Supplier No. PA582333
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPDPIIVPGN VTLSVMGSTS VPLSSPLKVD LVLEKEVAGL WIKIPCTDYI GSCTFEHFCD VLDMLIPTGE PCPEPLRTYG LPCHCPFKEG TYSLPKSEFV VPDLELPSWL TTGNYRIESV LSSSGKRLGC IKIAA Highest antigen sequence indentity to the following orthologs: Rat - 72%, Mouse - 72%.

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GM2A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GM2A
Gene Accession No. P17900
Gene Alias AA408702; AW215435; cerebroside sulfate activator protein; Ganglioside GM2 activator; Ganglioside GM2 activator isoform short; GM2 ganglioside activator; GM2 ganglioside activator protein; Gm2a; GM2-AP; SAP-3; shingolipid activator protein 3; sphingolipid activator protein 3
Gene Symbols GM2A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GM2A. Recombinant protein control fragment (Product #RP-89941).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2760
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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