Invitrogen™ GM2A Polyclonal Antibody

Catalog No.	Quantity
PIPA5109773	100 μL

Catalog No. PIPA5109773 Supplier Invitrogen™ Supplier No. PA5109773

Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLKKPSQLSS FSWDNCDEGK DPAVIRSLTL EPDPIIVPGN VTLSVMGSTS VPLSSPLKVD LVLEKEVAGL WIKIPCTDYI GSCTFEHFCD VLDMLIPTGE PCPEPLRTYG LPCHCPFKEG TYSLPKSEFV VPDLELPSWL TTGNYRIESV LSSSGKRLGC IKIAASLKGI.

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: GM2A
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.64 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GM2A
• Gene Accession No.: Q60648
• Gene Alias: AA408702; AW215435; cerebroside sulfate activator protein; Ganglioside GM2 activator; Ganglioside GM2 activator isoform short; GM2 ganglioside activator; GM2 ganglioside activator protein; Gm2a; GM2-AP; SAP-3; shingolipid activator protein 3; sphingolipid activator protein 3
• Gene Symbols: GM2A
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-193 of human GM2A (NP_000396.2).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14667, 282838
• Target Species: Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG