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Gma Dta TCR Mouse, anti-Human, R718, Clone: 11F2, BD OptiBuild™

Catalog No. BDB752023 Shop All BD Biosciences Products
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BDB752023 50 μg
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Catalog No. BDB752023 Supplier BD Biosciences Supplier No. 752023
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Description

Mouse Monoclonal Antibody

The 11F2 monoclonal antibody specifically reacts with a framework epitope of the γ/δ TCR. The γ/δ TCR is a heterodimeric glycoprotein that is noncovalently associated with the CD3 antigen complex. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. TCR γ/δ is present on a minor subset of T lymphocytes in peripheral blood, thymus, spleen, and lymph node. TCR γ/δ-positive T lymphocytes comprise 1% to 9% of normal peripheral blood lymphocytes and less than 2% of normal thymocytes. The 11F2 antibody is mitogenic for γ/δ-TCR-bearing T lymphocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Gma Dta TCR
Applications Flow Cytometry
Classification Monoclonal
Clone 11F2
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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