Invitrogen™ GMFB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551121

Catalog No. PA551121

Description

GMFB Polyclonal Antibody detects endogenous levels of GMFB protein.

This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF; being produced by the tumor cells.

Specifications

• Antigen: GMFB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gmfb
• Gene Alias: 3110001H22Rik; 3110001O16Rik; AI851627; C79176; D14Ertd630e; DNA for thyroid hormone receptor binding site (276bp); glia maturation factor beta; glia maturation factor beta-like protein; glia maturation factor, beta; GMF; Gmfb; GMF-beta
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2764, 63985, 81661
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P60983, Q63228, Q9CQI3
• Gene Symbols: Gmfb
• Immunogen: Synthesized peptide derived from the Internal region of human GMF-B (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov