Invitrogen™ GMFB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551787

Catalog No. PIPA551787

Description

Immunogen sequence: SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKN Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 94%.

This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF; being produced by the tumor cells.

Specifications

• Antigen: GMFB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gmfb
• Gene Alias: 3110001H22Rik; 3110001O16Rik; AI851627; C79176; D14Ertd630e; DNA for thyroid hormone receptor binding site (276bp); glia maturation factor beta; glia maturation factor beta-like protein; glia maturation factor, beta; GMF; Gmfb; GMF-beta
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2764, 63985, 81661
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P60983, Q63228, Q9CQI3
• Gene Symbols: Gmfb
• Immunogen: Recombinant protein corresponding to Human GMFB. Recombinant protein control fragment (Product #RP-89059).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG