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Invitrogen™ GMFB Polyclonal Antibody
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Catalog No. PIPA5121215
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100 μL
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PIPA5121215 100 μL
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Catalog No. PIPA5121215 Supplier Invitrogen™ Supplier No. PA5121215
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Description

Rabbit Polyclonal Antibody

Positive test controls include: LO2, U-87MG, MCF7, Mouse brain, Mouse kidney, Mouse liver, Rat kidney. Immunogen sequence: MSESLVVCDV AEDLVEKLRK FRFRKETNNA AIIMKIDKDK RLVVLDEELE GISPDELKDE LPERQPRFIV YSYKYQHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNK LVQTAELTKV FEIRNTEDLT EEWLREKLGF.

This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF; being produced by the tumor cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GMFB
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Gmfb
Gene Accession No. P60983, Q63228, Q9CQI3
Gene Alias 3110001H22Rik; 3110001O16Rik; AI851627; C79176; D14Ertd630e; DNA for thyroid hormone receptor binding site (276bp); glia maturation factor beta; glia maturation factor beta-like protein; glia maturation factor, beta; GMF; Gmfb; GMF-beta
Gene Symbols Gmfb
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human GMFB (NP_004115.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2764, 63985, 81661
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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