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Tocris Bioscience™ GN 44028
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Catalog No. 565510
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56-551-0 10 mg
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Catalog No. 56-551-0 Supplier Tocris Bioscience™ Supplier No. 5655/10
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Description

Potent HIF-1α inhibitor

GN 44028 is a potent HIF-1α inhibitor (IC50 = 14 nM). Inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. Cytotoxic to a range of cancer cell types in vitro.

Specifications

Chemical Name or Material N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
CAS 1421448-26-1
Quantity 10 mg
Target HIF Inhibitors
Molecular Formula C18N15N3O2
Formula Weight 305.33
Purity >98%
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