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Invitrogen™ GNA11 Polyclonal Antibody
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Catalog No. PIPA5102653
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100 μL
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PIPA5102653 100 μL
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Catalog No. PIPA5102653 Supplier Invitrogen™ Supplier No. PA5102653
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GNA11.

Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNA11
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GNA11
Gene Accession No. P21278, P29992, Q2XSV9, Q9JID2
Gene Alias Dsk7; E430025L19; FBH; FBH2; FHH2; g alpha-11; G protein subunit alpha 11; GA11; GNA11; Gna-11; G-protein subunit alpha-11; G-protein subunit GL2 alpha; Gq class; GTP-binding protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide binding protein alpha 11; guanine nucleotide binding protein, alpha 11; guanine nucleotide regulatory protein G alpha 11; guanine nucleotide-binding protein alpha 11; guanine nucleotide-binding protein alpha 11 subunit; guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11; HHC2; HYPOC2
Gene Symbols GNA11
Host Species Rabbit
Immunogen A synthesized peptide derived from human GNA11(Accession P29992), corresponding to amino acid residues T122-Y172.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14672, 2767, 733588, 81662
Target Species Human, Mouse, Rat, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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