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Invitrogen™ GNA11 Polyclonal Antibody
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Catalog No. PIPA531289
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100 μL
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PIPA531289 100 μL
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Catalog No. PIPA531289 Supplier Invitrogen™ Supplier No. PA531289
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Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, mouse kidney, rat brain. Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (97%), Dog (99%), Pig (97%), Chicken (100%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNA11
Applications Western Blot
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol; pH 7
Gene GNA11
Gene Accession No. P21278, P29992, Q9JID2
Gene Alias Dsk7; E430025L19; FBH; FBH2; FHH2; g alpha-11; G protein subunit alpha 11; GA11; GNA11; Gna-11; G-protein subunit alpha-11; G-protein subunit GL2 alpha; Gq class; GTP-binding protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide binding protein alpha 11; guanine nucleotide binding protein, alpha 11; guanine nucleotide regulatory protein G alpha 11; guanine nucleotide-binding protein alpha 11; guanine nucleotide-binding protein alpha 11 subunit; guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11; HHC2; HYPOC2
Gene Symbols GNA11
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human GNA11. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14672, 2767, 81662
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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