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Invitrogen™ GNA11 Polyclonal Antibody
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Catalog No. PIPA570664
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100 μL
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PIPA570664 100 μL
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Catalog No. PIPA570664 Supplier Invitrogen™ Supplier No. PA570664
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%.

Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNA11
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene GNA11
Gene Accession No. P21278, P29992
Gene Alias Dsk7; E430025L19; FBH; FBH2; FHH2; g alpha-11; G protein subunit alpha 11; GA11; GNA11; Gna-11; G-protein subunit alpha-11; G-protein subunit GL2 alpha; Gq class; GTP-binding protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide binding protein alpha 11; guanine nucleotide binding protein, alpha 11; guanine nucleotide regulatory protein G alpha 11; guanine nucleotide-binding protein alpha 11; guanine nucleotide-binding protein alpha 11 subunit; guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11; HHC2; HYPOC2
Gene Symbols GNA11
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human GNA11.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14672, 2767
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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