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Invitrogen™ GNAO1 Polyclonal Antibody
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Catalog No. PIPA5119825
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100 μL
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PIPA5119825 100 μL
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Catalog No. PIPA5119825 Supplier Invitrogen™ Supplier No. PA5119825
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Description

Rabbit Polyclonal Antibody

Positive Control: Rat brain tissue lysate, mouse brain tissue lysate, mouse hippocampus tissue lysate, human brain tissue lysate, human pancreas tissue. Subcellular Location: Cell membrane, Membrane.

Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNAO1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene GNAO1
Gene Accession No. P09471, P18872, P59215
Gene Alias alphaO; AW050213; DKFZp686O0962; EIEE17; G alpha o; G protein subunit alpha o1; Galphao; G-ALPHA-o; Gna0; Gnao; GNAO 1; Gnao1; Go alpha; GO2-q chimeric G-protein; GTP-binding protein alpha o; GTP-binding protein alpha-o subunit; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; guanine nucleotide binding protein, alpha O; guanine nucleotide binding protein, alpha O polypeptide 1; guanine nucleotide-binding protein G(o) subunit alpha; guanine nucleotide-binding regulatory protein 2; HLA-DQB1; RATBPGTPC
Gene Symbols GNAO1
Host Species Rabbit
Immunogen Recombinant protein within human GNAO1 aa 1-200.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14681, 2775, 50664
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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