Invitrogen™ GNAQ Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577989

Catalog No. PIPA577989

Description

Positive Control: 3xFlag-human GNAQ-transfected 293T Predicted Reactivity: Zebrafish (93%), Xenopus laevis (96%), Dog (100%), Pig (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.

Specifications

• Antigen: GNAQ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GNAQ
• Gene Alias: 1110005L02Rik; 6230401I02Rik; AA408290; AW060788; CMC1; Dsk1; Dsk10; G alpha q; G protein subunit alpha q; Galpha q; Galphaq; G-ALPHA-q; GAQ; GNAQ; gnaqa; Gq; GqI; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide binding protein alpha q subunit; guanine nucleotide binding protein, alpha q polypeptide; guanine nucleotide regulatory protein G alpha q; guanine nucleotide-binding protein alpha-q; Guanine nucleotide-binding protein G(q) subunit alpha; heterotrimeric guanine nucleotide-binding protein alpha q subunit; si:ch73-270f14.2; SWS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14682, 2776, 81666
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
• Gene Accession No.: P21279, P50148, P82471
• Gene Symbols: GNAQ
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GNAQ. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG