Invitrogen™ GNAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1724

Catalog No. PA1724

Description

PA1-724 detects rod transducin alpha (Tr alpha) from bovine outer rod segments and sheep retinal extract. PA1-724 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~38 kDa protein representing Tr alpha from sheep retinal extract. The PA1-724 immunizing peptide corresponds to amino acid residues 18-31 from human Tr alpha. This peptide (Cat. # PEP-153) is available for use in neutralization and control experiments.

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: GNAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GNAT1
• Gene Alias: CSNB1G; CSNBAD3; G protein subunit alpha transducin 1; GBT1; Gnat1; Gnat-1; GNATR; guanine nucleotide binding protein (G protein), alpha transducing 1; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; guanine nucleotide binding protein, alpha transducing 1; guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; Ird1; Ird2; irdc; irdr; rod-type transducin alpha subunit; Tr alpha; Tralpha; transducin; transducin alpha subunit; transducin alpha-1 chain; transducin alpha-subunit; transducin, rod-specific; transducin-alpha
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101121976, 2779, 281794
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P04695, P11488
• Gene Symbols: GNAT1
• Immunogen: Synthetic Peptide: K(18) L K E D A E K D A R T V K(31) C.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Bovine, Sheep
• Product Type: Antibody
• Isotype: IgG