Invitrogen™ GNB3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5143883	100 μg

Catalog No. PIPA5143883 Supplier Invitrogen™ Supplier No. PA5143883

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human HCCT tissue, human HCCP tissue, human Raji whole cell, rat brain tissue, rat kidney tissue, mouse brain tissue, mouse kidney tissue. IHC: human appendiceal adenocarcinoma tissue, human bladder epithelial carcinoma tissue, human breast cancer tissue, human liver cancer tissue, mouse brain tissue, rat brain tissue. ICC/IF: Hela cell. Flow: C6 cell, RAW2647 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Specifications

• Antigen: GNB3
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: GNB3
• Gene Accession No.: P16520, P52287, Q61011
• Gene Alias: CSNB1H; G protein beta-subunit; G protein subunit beta 3; G protein, beta-3 subunit; gbb3; GNB3; Gnb-3; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein, beta 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; guanine nucleotide-binding protein, beta-3 subunit; hypertension associated protein; transducin beta chain 3
• Gene Symbols: GNB3
• Host Species: Rabbit
• Immunogen: E.coli-derived human GNB3 recombinant protein (Position: A11-R49).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14695, 2784, 60449
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG