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Invitrogen™ GNB5 Polyclonal Antibody
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Catalog No. PIPA5119980
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100 μL
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PIPA5119980 100 μL
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Catalog No. PIPA5119980 Supplier Invitrogen™ Supplier No. PA5119980
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Description

Rabbit Polyclonal Antibody

Positive Control: HepG2 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, rat brain tissue, Hela. Subcellular Location: Membrane.

The Gb5 protein is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gb5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas Gb1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in the Gb's 1-4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNB5
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Gnb5
Gene Accession No. O14775, P62881, P62882
Gene Alias flail; flailer; flr; G protein subunit beta 5; G protein, beta subunit 5L; G protein, beta-5 subunit; GB5; GBB5; Gbeta5; GBS; Gnb5; guanine nucleotide binding protein (G protein), beta 5; guanine nucleotide binding protein (G protein), beta polypeptide 5; guanine nucleotide binding protein, beta 5; guanine nucleotide-binding protein subunit beta-5; guanine nucleotide-binding protein, beta subunit 5L; guanine nucleotide-binding protein, beta-5 subunit; hug; transducin beta chain 5
Gene Symbols Gnb5
Host Species Rabbit
Immunogen Recombinant protein within human Gbeta5 aa 1-200.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10681, 14697, 83579
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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