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Invitrogen™ GNE Polyclonal Antibody
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Catalog No. PIPA5101995
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Quantity:
100 μL
Catalog No. Quantity
PIPA5101995 100 μL
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Catalog No. PIPA5101995

Supplier: Invitrogen™ PA5101995

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GNE.

GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNE
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GNE
Gene Accession No. O35826, Q91WG8, Q9Y223
Gene Alias 2310066H07Rik; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; DMRV; GLCNE; glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; GNE; IBM2; ManAc kinase; N-acetylmannosamine kinase; N-acylmannosamine kinase; NM; Uae1; UDP-GlcNAc-2-epimerase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase; Uridine diphosphate-N-acetylglucosamine-2-epimerase
Gene Symbols GNE
Host Species Rabbit
Immunogen A synthesized peptide derived from human GNE(Accession Q9Y223), corresponding to amino acid residues A591-I641.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10020, 114711, 50798
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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