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  9. GNF 5, Tocris Bioscience™

GNF 5, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
778277-15-9
C20H17F3N4O3
418.376
IIQUYGWWHIHOCF-UHFFFAOYSA-N
gnf-5,gnf 5,unii-3zua56xmqq,n-2-hydroxyethyl-3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide,gnf5,3zua56xmqq,n-2-hydroxyethyl-3-6-4-trifluoromethoxy phenylamino pyrimidin-4-yl benzamide,n-2-hydroxyethyl-3-6-4-trifluoromethoxy anilino pyrimidin-4-yl benzamide,d0q8bk
44129660
N-(2-hydroxyethyl)-3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
C1=CC(=CC(=C1)C(=O)NCCO)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
This item is not returnable. View return policy
778277-15-9
C20H17F3N4O3
418.376
IIQUYGWWHIHOCF-UHFFFAOYSA-N
gnf-5,gnf 5,unii-3zua56xmqq,n-2-hydroxyethyl-3-6-4-trifluoromethoxy phenyl amino pyrimidin-4-yl benzamide,gnf5,3zua56xmqq,n-2-hydroxyethyl-3-6-4-trifluoromethoxy phenylamino pyrimidin-4-yl benzamide,n-2-hydroxyethyl-3-6-4-trifluoromethoxy anilino pyrimidin-4-yl benzamide,d0q8bk
44129660
N-(2-hydroxyethyl)-3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
C1=CC(=CC(=C1)C(=O)NCCO)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F

Description

Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

Selective, non-ATP competitive allosteric inhibitor of Bcr-Abl (IC50 = 220 nM for wild-type Abl). Binds the myristate-binding site of Abl. Acts in combination with nilotinib to inhibit T315I Bcr-Abl in vitro and in vivo. Analog of GNF 2 (Cat. No. 4399).
Quantity 50mg
Formula Weight 418.37
Chemical Name or Material GNF 5

Safety and Handling

Recommended Storage : Store at +4°C