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Invitrogen™ GNG8 Polyclonal Antibody
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Catalog No. PIPA5103880
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100 μL
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PIPA5103880 100 μL
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Catalog No. PIPA5103880 Supplier Invitrogen™ Supplier No. PA5103880
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GNG8.

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the γ as well as the α and β subunits and that preferential associations between members of subunit families increase G protein functional diversity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNG8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GNG8
Gene Accession No. P63077, P63078, Q9UK08
Gene Alias G protein subunit gamma 8; G(y)8; gamma-9; Ggamma 9; Ggamma9; Gng8; GNG9; GNGT9; G-protein gamma 8 subunit; guanine nucleotide binding protein (G protein), gamma 8; guanine nucleotide binding protein (G protein), gamma 8 subunit; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
Gene Symbols GNG8
Host Species Rabbit
Immunogen A synthesized peptide derived from human GNG8(Accession Q9UK08), corresponding to amino acid residues L36-L70.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14709, 245986, 94235
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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