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Invitrogen™ GNPNAT1 Polyclonal Antibody
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Catalog No. PIPA560788
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100 μL
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PIPA560788 100 μL
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Catalog No. PIPA560788 Supplier Invitrogen™ Supplier No. PA560788
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPMFDPSLLK EVDWSQNTAT FSPAISPTHP GEGLVLRPLC TADLNRGFFK VLGQLTETGV VSPEQFMKSF EHMKKSGDYY VTVVEDVTLG QIVATATLII EHKFIHSCAK RGRVEDVVVS DECRGKQLGK LLLSTLTLLS KKLNCYKITL ECLPQNVGFY KKFGYTVSEE NYMCRR Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNPNAT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GNPNAT1
Gene Accession No. Q96EK6, Q9JK38
Gene Alias AU017428; AU040593; EMeg32; Glucosamine 6-phosphate N-acetyltransferase; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; GNA1; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; Phosphoglucosamine acetylase; phosphoglucosamine transacetylase; Protein EMeg32; RGD1563144
Gene Symbols GNPNAT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GNPNAT1. Recombinant protein control fragment (Product #RP-88921).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 498486, 54342, 64841
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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