Invitrogen™ GNPNAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560788

Catalog No. PIPA560788

Description

Immunogen sequence: TPMFDPSLLK EVDWSQNTAT FSPAISPTHP GEGLVLRPLC TADLNRGFFK VLGQLTETGV VSPEQFMKSF EHMKKSGDYY VTVVEDVTLG QIVATATLII EHKFIHSCAK RGRVEDVVVS DECRGKQLGK LLLSTLTLLS KKLNCYKITL ECLPQNVGFY KKFGYTVSEE NYMCRR Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).

Specifications

• Antigen: GNPNAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GNPNAT1
• Gene Alias: AU017428; AU040593; EMeg32; Glucosamine 6-phosphate N-acetyltransferase; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; GNA1; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; Phosphoglucosamine acetylase; phosphoglucosamine transacetylase; Protein EMeg32; RGD1563144
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 498486, 54342, 64841
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96EK6, Q9JK38
• Gene Symbols: GNPNAT1
• Immunogen: Recombinant protein corresponding to Human GNPNAT1. Recombinant protein control fragment (Product #RP-88921).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG