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GnRHR Antibody (GNRHR/768), Novus Biologicals™
SDP

Mouse Monoclonal Antibody

$268.00 - $526.00

Specifications

Antigen GnRHR
Clone GNRHR/768
Concentration 0.2mg/mL
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 1 - 2 ug/ml
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24530000
SDP
View Documents
Novus Biologicals
NBP2453000.02MG
0.02 mg
Each for $268.00
Only null left
Add to Cart
 
NBP24530001
SDP
View Documents
Novus Biologicals
NBP2453000.1MG
0.1 mg
Each for $526.00
Only null left
Add to Cart
 
NBP24530002
SDP
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Novus Biologicals
NBP2453000.2MG
0.2 mg N/A N/A N/A
Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

GnRHR Monoclonal specifically detects GnRHR in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

GnRHR
0.2mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
Mouse
Human
GnRH receptor, GnRH-R, GNRHR1, gonadotropin-releasing hormone (type 1) receptor 1, gonadotropin-releasing hormone receptor, GRHR, leutinizing-releasing hormone receptor, LHRHRleutinizing hormone releasing horomone receptor, LRHR, luliberin receptor, type I GnRH receptor
Recombinant full-length human GNRHR protein
Primary
Store at 4C.
GNRHR/768
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 1 - 2 ug/ml
Monoclonal
Purified
RUO
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
2798
IgG1 κ
Protein A or G purified
Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.
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