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Invitrogen™ GnRHR Polyclonal Antibody
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Catalog No. PIPA533597
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50 μg
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PIPA533597 50 μg
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Catalog No. PIPA533597 Supplier Invitrogen™ Supplier No. PA533597
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gibbon (100%) Gorilla, Monkey, Dog, Elephant, Panda (95%) Marmoset, Bovine, Horse, Pig (90%).

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GnRHR
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Gnrhr
Gene Accession No. P30968
Gene Alias GH1; GnRH receptor; Gnrhr; gnRH-R; GNRHR1; gonadotropin releasing hormone receptor; gonadotropin releasing hormone receptor type-I; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor; GRHR; growth hormone; HH7; HHG; hypergonadotropic hypogonadism; LCGR; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; LGR2; LH/CGR; LH/CG-R; LHCGR; LHR; Lh-rh receptor; Lhrhr; LRHR; LSH-R; luliberin receptor; Luteinizing hormone receptor; luteinizing hormone/choriogonadotropin receptor; lutropin/choriogonadotropin receptor; lutropin-choriogonadotropic hormone receptor; type I GnRH receptor; Type I GNRHR1; ULG5
Gene Symbols Gnrhr
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GNRHR.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2798
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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