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GNRHR Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501732617 Shop All Proteintech Group Inc Products
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50-173-2617 150 μL
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Catalog No. 50-173-2617 Supplier Proteintech Group Inc Supplier No. 199501AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody only recognizes isoform 1 of GNRHR. The predicted unmodified molecular weight of the human GNRHR is ∽38 kDa, the larger band (50-60 kDa) is likely to represent a glycosylated form of GNRHR.

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene.

Specifications

Antigen GNRHR
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GNRHR
Gene Accession No. P30968, Q01776
Gene Alias GnRH R, GnRH receptor, GNRHR, GNRHR1, GRHR, LHRHR, LRHR
Gene Symbols GNRHR
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14715, 2798
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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