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ABCA4, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89115223 Shop All Abnova Corporation Products
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89-115-223 100 μg
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Catalog No. 89-115-223 Supplier Abnova Corporation Supplier No. PAB11617
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Description

Goat polyclonal antibody raised against synthetic peptide of ABCA4.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq

Sequence: EPECPGPQLNTGTQ

Specifications

Antigen ABCA4
Applications ELISA
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of ABCA4.
Dilution ELISA (1:32000) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene ABCA4
Gene Accession No. NP_000341.2
Gene Alias ABC10/ABCR/ARMD2/CORD3/DKFZp781N1972/FFM/FLJ17534/RMP/RP19/STGD/STGD1
Gene Symbols ABCA4
Host Species Goat
Immunogen A synthetic peptide corresponding to amino acids 1336-1349 of human ABCA4.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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