ABCC5, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-295	100 μg

Catalog No. 89-133-295 Supplier Abnova Corporation Supplier No. PAB7484

Description

Goat polyclonal antibody raised against synthetic peptide of ABCC5.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq

Sequence: KDIDIGKEYIIP-C

Specifications

• Antigen: ABCC5
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ABCC5.
• Dilution: ELISA (1:32000) Western Blot (0.5-1.5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: ABCC5
• Gene Accession No.: NP_005679.2;NP_001018881.1
• Gene Alias: ABC33/DKFZp686C1782/EST277145/MOAT-C/MOATC/MRP5/SMRP/pABC11
• Gene Symbols: ABCC5
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human ABCC5.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10057
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_005679.2, NP_001018881.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only