ACHE Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-654	100 μg

Catalog No. 89-132-654 Supplier Abnova Corporation Supplier No. PAB6747

Description

Goat polyclonal antibody raised against synthetic peptide of ACHE.

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq

Sequence: QFDHYSKQDRCSDL

Specifications

• Antigen: ACHE
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ACHE.
• Dilution: ELISA (1:64000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: ACHE
• Gene Accession No.: NP_000656.1
• Gene Alias: ARACHE/N-ACHE/YT
• Gene Symbols: ACHE
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human ACHE.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 43
• Test Specificity: This antibody is expected to recognize isoform NP_000656 only (the ubiquitously expressed, hydrophillic form).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only