AGTR1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-969	100 μg

Catalog No. 89-132-969 Supplier Abnova Corporation Supplier No. PAB7122

Description

Goat polyclonal antibody raised against synthetic peptide of AGTR1.

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq

Sequence: C-EIQKNKPRNDDIFK

Specifications

• Antigen: AGTR1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of AGTR1.
• Dilution: ELISA (1:32000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: AGTR1
• Gene Accession No.: NP_000676.1;NP_004826.2;NP_033611.1;NP_114038.1;NP_114438.1
• Gene Alias: AG2S/AGTR1A/AGTR1B/AT1/AT1B/AT1R/AT2R1/AT2R1A/AT2R1B/HAT1R
• Gene Symbols: AGTR1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human AGTR1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 185
• Test Specificity: All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only