AIRE Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-899	100 μg

Catalog No. 89-132-899 Supplier Abnova Corporation Supplier No. PAB7040

Description

Goat polyclonal antibody raised against synthetic peptide of AIRE.

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). [provided by RefSeq

Sequence: C-KDVDLSQPRKGRKP

Specifications

• Antigen: AIRE
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of AIRE.
• Dilution: ELISA (1:32000) Western Blot (0.5-1 ug/mL) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: AIRE
• Gene Accession No.: NP_000374.1
• Gene Alias: AIRE1/APECED/APS1/APSI/PGA1
• Gene Symbols: AIRE
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human AIRE.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 326
• Test Specificity: This antibody is expected to recognize isoform 1 (NP_000374.1) only.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only