ALDH2, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ALDH2.

Manufacturer:  Abnova Corporation PAB18541

Catalog No. 89-120-100

Description

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq

Sequence: C-DETQFKKILGYIN

Specifications

• Antigen: ALDH2
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of ALDH2.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene Accession No.: NP_000681.2
• Gene Alias: ALDH-E2|ALDHI|ALDM|MGC1806
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 217

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:8000) Sandwhich ELISA (1-2 ug/mL) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ALDH2
• Format: Liquid
• Gene Symbols: ALDH2
• Immunogen: A synthetic peptide corresponding to internal region of human ALDH2.
• Quantity: 100 ug
• Storage Requirements: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Murine, Rat

For Research Use Only