ALS2, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-156	100 μg

Catalog No. 89-132-156 Supplier Abnova Corporation Supplier No. PAB6113

Description

Goat polyclonal antibody raised against synthetic peptide of ALS2.

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: LKACYYQIQREKLN

Specifications

• Antigen: ALS2
• Applications: ELISA, Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ALS2.
• Dilution: ELISA (1:8000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: ALS2
• Gene Accession No.: NP_065970.2
• Gene Alias: ALS2CR6/ALSJ/FLJ31851/IAHSP/KIAA1563/MGC87187/PLSJ
• Gene Symbols: ALS2
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human ALS2.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57679
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only